Hudak Scientific Consulting, LLC

CV

JHudak Resume 2025Download

Jason Hudak, Ph.D., PMP

Consultant/CSO/PMP

Summary of Qualifications

  • 16+ years experience in life sciences drug discovery, project management and operations coordination
  • Proven success in leadership, motivation, and organization across R&D, Clinical, Regulatory and Admin
  • Thorough in vitro and in vivo oncology, immuno-oncology, cell biology, microbiology and chemistry experience
  • Certified PMP with expertise in contemporary management methodologies pertinent to biotech operations
  • Strong public scientific communicator with a deliverable/risk, scientist-focused management approach

Professional Experience

Fractional CSO

July 2025 – present

Milieu, Inc, Ann Arbor, MI

  • Lead the company’s scientific vision, strategy, and innovation pipeline in skin microbiome research and biotechnology.
  • Oversee multidisciplinary R&D programs spanning discovery, preclinical, and translational development of novel skincare and microbiome-based products.
  • Ensure the rigorous scientific integrity, compliance, and quality assurance of all research and development activities.
  • Support fundraising, grant writing, and investor engagement by providing clear data-driven scientific direction and securing R&D funding.
  • Represent Milieu at scientific conferences, investor meetings, and in media, communicating the company’s science, innovation, and impact.

Lead Scientific Consultant                                                                                         

Nov 2024 – present

Hudak Scientific Consulting, LLC, Ann Arbor, MI

  • Founded and manage my firm specializing in strategic preclinical road-mapping and experimental streamlining
  • Conduct thorough literary reviews to inform risk-based decision-making and optimize R&D processes for clients
  • Align client requirements to design tailored solutions, leading to improvements in efficiency and cost savings

Scientific Program Manager                            

May 2023 – Aug 2023

University of California, San Francisco, CA

  • Oversaw communication, budgeting and delivery across 45 global partners within a $200M NIH grant
  • Formed a chemical repository, matching AI database and compound storage workflow at UCSF
  • Self-ensured intellectual property and NDA documentation was established across multiple organizations and legal teams

Principal Immunology Scientist/Consultant Bacterial Cell Therapy 

June 2022 – Mar 2023

ResVita Bio, Berkeley, CA

  • Leveraged past experiences in Scrumban methodology to chart the company’s strategic direction in cell-based therapeutics
  • Directed company recruitment and training for research staff, acting as primary liaison with CEO and leadership
  • Established facility SOPs, set the research agenda, and defined corporate culture as the inaugural hire

Event Director and Nonprofit Sponsorship Manager                                                  

Aug 2019 – Nov 2023

BAAAHS Organization and Queens of the Castro, San Francisco, CA

  • Responsible for recruitment and contact with all sponsors and donors for non-profit fundraising events
  • Spearheaded communication, volunteer recruitment, and fundraising for many LGBTQ community/activist events
  • As event director, scheduled and managed 24+ events within a single week across multiple organizations

Senior Scientist RNA Genetic Therapeutics Mucosal Biology   

Feb 2021 – Mar 2022

DNAlite Therapeutics, San Francisco, CA

  • Presented BD material to investors and partners, showcasing self-produced bioanalytic data
  • Executed and ran a successful business plan for preclinical/clinical development of new therapeutic targets

Senior Scientist Bacterial Microbiome Cell Therapy   

June 2018 – Feb 2021

Assembly Biosciences, South San Francisco, CA

  • Employed a Kanban model to manage a hit-to-lead discovery program ending in approved FDA IND application
  • Identified and developed bioanalytical methods to pair R&D and GLP quality control CMC team project plans
  • Led planning of site relocation/procurement including off-site vivarium space and coordinating oncology CROs

Scientist Microbiome Oncology  

Jan 2017 – June 2018

Evelo Biosciences, Cambridge, MA            

  • As project lead, developed chemistry/genomic analytic methods to track microbial strains and components within the host immune system in vivo to define biodistribution/pharmacokinetic profiles for funding and IND applications

CRI Irvington Postdoctoral Fellow

Sept 2013 – Sept 2016

Harvard Medical School, Prof. Dennis Kasper, Boston, MA          

  • Applied click chemistry to label immunomodulatory molecules from live commensal bacteria and track changes in bacterial uptake within immune cells in GI diseases and colitis-associated colorectal cancer in vivo
  • Authored fellowship and grant applications securing funding from the Cancer Research Institute for salary ($160,000/3 years) and with the DOD ($2,542,500/3 years) for a collaborative research project

Protein Chemistry Intern/Consultant   

2011-2012

Redwood Bioscience Inc. (now Catalent SMARTag Division), Emeryville, CA

  • Worked within a team of chemists, biologists, and business professionals to implement click chemistry in antibody-drug conjugates

Skills 

Management Scrumban (Scrum/Kanban) approach, Lean Six Sigma methodology, resource allocation, CRO/procurement management, team building, leadership, oral/written technical communication, presentation skills, data analysis, risk management, budget management, grant writing, conflict resolution, process improvement, lab management, lab policy, FDA regulation, cGMP review, Gantt chart

Immunology/Chemistry Primary human/mouse cell culture, animal disease models, oncology, genomics/NGS, gene editing, mRNA transfection, protein chemistry, glycobiology, FACS, ELISA, ELISPOT, MSD, QRT-PCR, immune cell assays (T, B, NK, DC, MO), proteomics, PTM analysis, PK/PD, biodistribution, biologics, SAR

Software Skills/Data Analysis Microsoft Project, Powerpoint, Excel, Prism, LIMS, ELN, Jira, Asana, Smartsheet

Education

Project Management Professional (PMP) Certification

2025

Project Management Institute, ID# 4045992

Ph.D. Chemistry/Chemical Biology

2007-2013

University of California, Berkeley, CA           

PI: Carolyn R. Bertozzi, Thesis: “Protein and Cell Surface Engineering with Oxime Conjugates”

B.S. Chemistry with Honors

2003-2007

Case Western Reserve University, Cleveland, OH

summa cum laude, Minors: Biology, Spanish

Publications

  1. Hudak, J. E.; Alvarez, D.; Skelly, A.; Andrian, U. H. von; Kasper, D. L. “Illuminating vital surface molecules of symbionts in health and disease” Nat. Microbiol. 2017, 2, nmicrobiol201799.
  2. Hudak, J. E.; Belardi, B.D.; Solania, S. K.; Appel, M.; Robinson, P.V.; Bertozzi, C. R. “Piperidine-Based Glycodendrons as Protein N-Glycan Prosthetics” Biorg. Med. Chem. 2016, 24, 4791-4800.
  3. Geva-Zatorskya, N.; Alvareza, D.; Hudak, J. E.; Reading N. C.; Erturk-Hasdemir, D.; Dasgupta, S.; von Andrian, U. H.; Kasper, D. L. “In vivo imaging and tracking of host-microbiota interactions via metabolic labeling of gut anaerobic bacteria” Nat. Med. 2015, 21, 1091–110.
  4. Paszek, M. J.; Dufort, C. C; Rossier, O.; Bainer, R.; Mouw, J. K.; Godula, K.; Hudak, J. E.; et al. “The cancer cell glycocalyx mechanically primes integrin-mediated growth and survival.” Nature 2014, 511, 319-25,
  5. Hudak, J. E.; Canham, S. M.; Bertozzi, C. R. “Glycocalyx Engineering Reveals a Siglec-Based Mechanism for NK Cell Immunoevasion” Nat. Chem. Biol. 2014, 10, 69-75.
  6. Hudak, J. E.; Bertozzi, C. R. “Glycotherapy: New Advances Inspire a Reemergence of Glycans in Medicine” Chem. Biol. 2014, 21, 16-37.
  7. Hudak, J. E.; Barfield, R. M.; de Hart, G. W.; Grob, P.; Nogales, E.; Bertozzi, C. R.; Rabuka, D. “Synthesis of Heterobifunctional Protein Fusions Using Copper-Free Click Chemistry and the Aldehyde Tag” Angew. Chem. Int. Ed. 2012, 51, 4161-4165.
  8. Hudak, J. E.; Yu, H. H.; Bertozzi, C. R. “Protein Glycoengineering Enabled by the Versatile Synthesis of Aminooxy Glycans and the Genetically Encoded Aldehyde Tag” J. Am. Chem. Soc. 2011, 133, 16127–16135.
  9. Fishovitz, J.; Li, M.; Frase, H.; Hudak, J.; Craig, S.; Ko, K.; Berdis, A. J.; Suzuki, C. K.; Lee, I. “Active-site-directed chemical tools for profiling mitochondrial Lon protease” ACS Chem. Biol. 2011, 6, 781–788.
  10. Patterson-Ward, J.; Tedesco, J.; Hudak, J.; et al. “Utilization of synthetic peptides to evaluate the importance of substrate interaction at the proteolytic site of Escherichia coli Lon protease.”Biochim Biophys Acta. 2009, 1794, 1355-63.
  11. Frase, H.; Hudak, J.; and Lee, I. “Identification of the proteasome inhibitor MG262 as a potent ATP-dependent inhibitor of the Salmonella enterica serovar Typhimurium Lon protease.” Biochemistry. 2006, 45, 8264-74. 

Patent Filings

  • Goodman, B.; Hudak, J. “Polymer compositions.” PCT/US2018/044053 filed 27 Jul 2018. WO2019023555A1 published 31 Jan 2019 
  • Argueta, S; Bodmer, M; Francisco-Anderson, L; Gardner, H; Goldberg, M.F.; Hudak, J.; Kashyap, S.; Parameswaran, P.; Ponichtera, H.; Sandy, P. “Inducing immune effects using bacteria of the genus bifidobacterium.” PCT/US2020/044402 filed 31 Jul 2020. WO2021022110A1 published 2 Feb 2021 
  • Akbari, P.; Akin, A.; Feigelman, R.; Herber, W.; Hudak, J.; Ma, J.; Papkoff, J.; Wong, L. “Compositions comprising bacterial species and methods related thereto.” PCT/US2020/048627 filed 28 Aug 2020. WO2021041981A1 published 4 Mar 2021 
  • Papkoff, J.; Ma, J.; Hudak, J.; Nguyen, L. “Compositions comprising bacterial species and methods related thereto.” PCT/US2020/067674 filed 31 Dec 2020. WO2021138562A1 published 8 Jul 2021 
  • Papkoff, J.; Ma, J.; Hudak, J.; Nguyen, L. “Compositions comprising bacterial species and methods related thereto.” PCT/US2020/067685 filed 31 Dec 2020. WO2021138571A1 published 8 Jul 2021
  • Papkoff, J.; Ma, J.; Hudak, J.; Nguyen, L. “Compositions comprising bacterial species and methods related thereto.” PCT/US2020/067676 filed 31 Dec 2020. WO2021141828A1 published 15 Jul 2021